Minimizing the cost of hydrogen production through dynamic polymer electrolyte membrane electrolyzer operation
Ginsberg, M., Venkatraman, M., Esposito, D., & Fthenakis, V.
(2022)
I'm Maya Venkatraman, a Research Software Engineer at the AlQuraishi Laboratory at Columbia University.
Currently, I work on developing a billion-parameter genome language model trained on prokaryotic DNA. My work spans the full ML research stack—from data curation and infrastructure to model architecture design, training, and biological benchmarking. I am particularly interested in the challenges of modeling biological sequences at single-nucleotide resolution and ultra-long context lengths, which push the boundaries of current transformer architectures.
In parallel to my research, I am pursuing a part-time Master's in Statistics at Columbia University, supported by the departmental MA2PhD Fellowship, which identifies students likely to pursue doctoral study in computational fields. I believe that rigorous statistical training is essential for advancing interpretable, efficient, and principled models in computational biology.
My interests within machine learning are both deep and broad, and I am considering multiple areas of focus for my PhD. I am particularly excited about the potential of diffusion models for protein design, as well as the use of reinforcement learning to guide exploration of conformational space. I am also drawn to novel AI techniques such as Hierarchical Dynamic Chunking from the Gu lab, valuing the idea of end-to-end, jointly optimized models that require less heuristic intervention. I believe that approaches like these will be especially relevant in biology, where data is inherently hierarchical, noisy, and context-dependent. I also see interpretability as a fascinating frontier in biological modeling, potentially enabling researchers to reverse engineer molecular contacts or mechanisms from patterns in model attention.
In the past, I worked at Google Research, applying computer vision to dermatologic image classification (Derm on Lens). I also contributed on a 20% basis to genomics projects, including DeepVariant and DeepNull. Before that, I worked at YouTube Trust and Safety, building infrastructure for detecting abusive user behavior.
Core member of team developing a billion-parameter prokaryotic genome language model (GLM) by scaling a BERT-style transformer with an MLM objective. Explored selective learning and distributed training methods to enhance model training efficiency. Designed and implemented novel biological benchmarks and reformulated existing benchmarks to assess scaling laws in our GLM. Co-developed a novel architecture for co-generating protein structure and sequence using diffusion.
Research Advisor: Mohammed AlQuraishi, Assistant Professor of Systems Biology & Computer Science
Department Profile: Columbia Systems Biology
L4 SWE
2023 - 2024
Applied computer vision techniques to classify skin lesions through the "Derm on Lens" project. Led launch of the new model, supporting first-ever ophthalmologic image classification. Contributed to research at the intersection of deep learning and genomics, including DeepVariant and DeepNull.
Research Advisors: Farhad Hormozdiari and Kishwar Shafin
Featured in U.S. Dermatology Partners: "I Used Google Lens To Check for Skin Cancer—Here's What Happened"
Project releases: DeepVariant Release Notes
L3 → L4 SWE
2021 - 2023
Built ML infrastructure to detect abusive user behavior, improving platform safety at scale.
In a past life, I worked in a chemical engineering lab, developing computational models (a mix of algorithms and optimization) to demonstrate how hydrogen electrolysis can be performed at minimized cost.
Advisor: Daniel Esposito, Associate Professor of Chemical Engineering
Ginsberg, M., Venkatraman, M., Esposito, D., & Fthenakis, V.
(2022)Ginsberg, M., Zhang, Z., Atia, A., Venkatraman, M., et al.
(2022)Sayres, R., Jain, A., Venkatraman, M., et al.
Expected 2025
Selected as a recipient of the National Science Foundation's (NSF) Computer and Information Science and Engineering Graduate Fellowship (CSGrad4US), which provides three years of full funding for my PhD in computer science.
Featured on Columbia University Undergraduate Research & Fellowships
DeepVariant v1.9.0 achieves ~20% runtime reduction and improved accuracy with the new HG002-T2T truth set. The latest release includes faster inference through optimized tensor handling and updated training schemes; I contributed through exploration of novel model architectures, hyperparameter tuning, and training dataset compositions.
Project details: DeepVariant Release Notes
Selected as Salutatorian of Columbia Engineering's Class of 2022, recognizing exceptional academic achievement throughout undergraduate studies in computer science.
Received Honorable Mention in the National Center for Women & Information Technology (NCWIT) Collegiate Award for the project "Adding YouTube HLS Output to OBS (Open Broadcaster Software)" -- recognizing outstanding computing accomplishments and technical innovation.
Featured on NCWIT Aspirations in Computing
Recognized by Columbia University for improving inclusivity in computer science classes and demonstrating leadership as head teaching assistant, coordinating teaching staff during the early pandemic to ensure positive student experience.
Featured on Columbia College & Engineering
Departmental award from Columbia University's Computer Science Department, recognizing majors who have demonstrated exceptional achievement in the field.
Featured in Columbia CS Highlights 2021
Recognized as a National Merit Finalist for receiving a perfect score on the PSAT and selected as one of six Newton students to win the scholarship, chosen from over 15,000 finalists nationwide.
Featured in Newton Patch News
Selected as one of four female students in Massachusetts as a semifinalist for the U.S. Presidential Scholars Program. This award is one of the nation's highest honors for high school students, recognizing superior academic achievement and leadership potential.
Listed in U.S. Department of Education Official Semifinalists List
Connect with me on LinkedIn or email me at maya.venkatraman1@gmail.com